|
|
| Nomenclature |
|
Symbol:
|
Cd36obl
|
|
Name:
|
CD36 antigen;
oblivious
|
|
MGI ID: |
MGI:3573941 |
|
Synonyms: |
Cd36m1Btlr, obl |
|
Gene:
|
Cd36
Location:
Chr5:17781690-17888959 bp, - strand
Genetic Position: Chr5,
8.11 cM
|
|
Mutation
origin |
|
Strain of Origin:
|
C57BL/6
|
|
Mutation
description |
|
Allele
Type: | |
Chemically induced (ENU) |
|
Mutation: | |
Single point mutation |
| |
|
Mutation details: This allele contains a T to A point mutation at position 1022 in exon 11, creating an early stop codon and removing 133 residues from the C-terminus of the polypeptide chain. Loss of these amino acids prevented formation of the second of two transmembrain domains. Western blot against antibodies for the amino terminal showed an absence of protein in whole cell extracts and supernatant. (J:96018)
|
|
Inheritance: | |
Recessive |
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:96018
Hoebe K et al.,
"CD36 is a sensor of diacylglycerides."
Nature 2005 Feb 3;433(7025):523-7
|
|
All: |
4 reference(s)
|
|
Analysis Tools
