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| Nomenclature |
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Symbol:
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Del(11Cops3-Rnf112)1Jrl
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Name:
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deletion, Chr 11, James R Lupski 1
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MGI ID: |
MGI:3521985 |
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Synonyms: |
Del(11Csn3-Zfp179)1Jrl, Del1Jrl, df(11)17 |
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Gene:
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Del(11Cops3-Rnf112)1Jrl
Location:
unknown
Genetic Position: Chr11,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:83302
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (other) |
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Mutation: | |
Intergenic deletion |
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Mutation details: A deletion between Cops3 and Rnf112 was engineered in ES cells by targeted insertion of complementary partial Hprt-loxP constructs at each site. Cre recombinase actived deleted the intervening region and reconstructed the Hprt minigene for selection purposes. (J:83302)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:83302
Walz K et al.,
"Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance."
Mol Cell Biol 2003 May;23(10):3646-55
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All: |
8 reference(s)
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Analysis Tools
