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| Nomenclature |
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Symbol:
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Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy
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Name:
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transgene insertion, Winston C Y Yu
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MGI ID: |
MGI:3510918 |
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Synonyms: |
SIRIUS-ABCA1 |
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Transgene:
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Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of the mouse Rnu6 promoter, a loxP site, a CMV promoter, EGFP, and an Abca1 siRNA. Without cre mediated recombination only EGFP is expressed. After cre mediated recombination the Abca1 siRNA is expressed. Six founders were generated. (J:93624)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:93624
Chang HS et al.,
"Using siRNA technique to generate transgenic animals with spatiotemporal and conditional gene knockdown."
Am J Pathol 2004 Nov;165(5):1535-41
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All: |
1 reference(s)
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Analysis Tools
