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| Nomenclature |
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Symbol:
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Myf6tm1(cre)Mrc
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Name:
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myogenic factor 6;
targeted mutation 1, Mario R Capecchi
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MGI ID: |
MGI:3487371 |
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Synonyms: |
Myf6-Cre, Myf6ICNm, Myf6-NN- |
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Gene:
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Myf6
Location:
Chr10:107492860-107494729 bp, - strand
Genetic Position: Chr10,
55.96 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:93444
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: An IRES-Cre was inserted in the 3' UTR to allow bicistronic expression of Myf6 and Cre. An FRT flanked neo was excised upon crossing with transgenic mice expressing FLPe. (J:93444)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Myf6 Mutation:
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2 strains or lines available |
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Notes |
Expression of the endogenous gene is normal.
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| References |
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Original: |
J:93444
Keller C et al.,
"Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function."
Genes Dev 2004 Dec 1;18(21):2614-26
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All: |
6 reference(s)
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Analysis Tools
