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| Nomenclature |
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Symbol:
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Tnfaip3tm1Ama
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Name:
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tumor necrosis factor, alpha-induced protein 3;
targeted mutation 1, Averil Ma
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MGI ID: |
MGI:3055173 |
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Synonyms: |
A20- |
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Gene:
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Tnfaip3
Location:
Chr10:19000910-19015657 bp, - strand
Genetic Position: Chr10,
8.08 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:92931
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A PGK-neo in reverse transcription orientation replaced exons 1-4, encompassing the ATG initiation codon and residues 1-246. (J:92931)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tnfaip3 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:92931
Lee EG et al.,
"Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice."
Science 2000 Sep 29;289(5488):2350-4
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All: |
7 reference(s)
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Analysis Tools
