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| Nomenclature |
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Symbol:
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Artm1.1Chc
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Name:
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androgen receptor;
targeted mutation 1.1, Chawnshang Chang
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MGI ID: |
MGI:2687199 |
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Synonyms: |
AR-, ARKO, GARKO |
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Gene:
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Ar
Location:
ChrX:98149721-98323215 bp, + strand
Genetic Position: ChrX,
42.82 cM
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Immunostaining of androgen receptor and histological analysis of testes of Artm1.1Chc/Y mice
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:81789
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The loxP flanked region including exon 2 was excised from Artm1Chc via cre mediated recombination. Exon 2 encodes the second zinc finger of the DNA-binding domain. (J:81789)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:81789
Yeh S et al.,
"Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues."
Proc Natl Acad Sci U S A 2002 Oct 15;99(21):13498-503
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All: |
9 reference(s)
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Analysis Tools
