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| Nomenclature |
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Symbol:
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Ext1tm1Yama
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Name:
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exostoses (multiple) 1;
targeted mutation 1, Yu Yamaguchi
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MGI ID: |
MGI:2682061 |
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Synonyms: |
Ext1f, Ext1flox |
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Gene:
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Ext1
Location:
Chr15:53064038-53346159 bp, - strand
Genetic Position: Chr15,
20.0 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:86465
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Parent Cell Line:
| Lex-1 (ES Cell) |
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Strain of Origin:
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129S5/SvEvBrd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: The coding region of exon 1 was flanked by single loxP sites in the 5' untranslated region of exon 1 and in intron 1. The targeting vector contained a frt-flanked neomycin cassette in intron 1, though this selection cassette was removed via in vivo FLP-mediated recombination. (J:86465)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ext1 Mutation:
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20 strains or lines available |
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| References |
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Original: |
J:86465
Inatani M et al.,
"Mammalian brain morphogenesis and midline axon guidance require heparan sulfate."
Science 2003 Nov 7;302(5647):1044-6
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All: |
16 reference(s)
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Analysis Tools
