|
|
| Nomenclature |
|
Symbol:
|
Cplx1tm1Rmnd
|
|
Name:
|
complexin 1;
targeted mutation 1, Christian Rosenmund
|
|
MGI ID: |
MGI:2679624 |
|
Synonyms: |
Cplx1-, CPX I- |
|
Gene:
|
Cplx1
Location:
Chr5:108518554-108550024 bp, - strand
Genetic Position: Chr5,
53.17 cM
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:86365
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
Not Specified
|
|
Mutation description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: The first coding exon was replaced by a neomycin resistance gene. Western blot analysis of adult brains demonstrated the abolition of protein product expression. (J:86365)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Cplx1 Mutation:
|
3 strains or lines available |
|
| References |
|
Original: |
J:86365
Reim K et al.,
"Complexins regulate a late step in Ca2+-dependent neurotransmitter release."
Cell 2001 Jan 12;104(1):71-81
|
|
All: |
10 reference(s)
|
|