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| Nomenclature |
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Symbol:
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Zfp423nur12
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Name:
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zinc finger protein 423;
neurological 12
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MGI ID: |
MGI:2671784 |
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Synonyms: |
ataxia1, nurm12Jus |
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Gene:
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Zfp423
Location:
Chr8:87661810-87959595 bp, - strand
Genetic Position: Chr8,
42.29 cM, cytoband C4
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Ataxia and malformation in Zfp423nur12/Zfp423nur12 mice
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at the Baylor College of Medicine. A C-to-T transition mutation in the fourth exon results in the introduction of a premature stop codon. Western blot analysis showed that no detectable protein was expressed from this allele. (J:114758)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Phenotypic Similarity to Human Syndrome: Cerebellar vermis hypoplasia (J:114758).
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| References |
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Original: |
J:85113
Kile BT et al.,
"Functional genetic analysis of mouse chromosome 11."
Nature 2003 Sep 4;425(6953):81-6
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All: |
3 reference(s)
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Analysis Tools
