|
|
| Nomenclature |
|
Symbol:
|
Insl3tm1Imad
|
|
Name:
|
insulin-like 3;
targeted mutation 1, Ibrahim M Adham
|
|
MGI ID: |
MGI:2661997 |
|
Synonyms: |
Insl3-, Leyl- |
|
Gene:
|
Insl3
Location:
Chr8:71689214-71690575 bp, + strand
Genetic Position: Chr8,
34.43 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:83429
|
|
Parent Cell Line:
| MPI-II (ES Cell) |
|
Strain of Origin:
|
129S2/SvPas
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: The 2 exons that comprise the gene were replaced with a neomycin selection cassette inserted by homologous recombination. Transcript was undetected by Northern blot analysis of testicular mRNA obtained from homozygous mutant males. (J:83429)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Insl3 Mutation:
|
1 strain or line available |
|
| References |
|
Original: |
J:83429
Zimmermann S et al.,
"Targeted disruption of the Insl3 gene causes bilateral cryptorchidism."
Mol Endocrinol 1999 May;13(5):681-91
|
|
All: |
7 reference(s)
|
|
Analysis Tools
