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| Nomenclature |
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Symbol:
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Foxp3tm1.1Ayr
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Name:
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forkhead box P3;
targeted mutation 1.1, Alexander Y Rudensky
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MGI ID: |
MGI:2654936 |
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Synonyms: |
Foxp3-, Foxp3-GFP, Foxp3 KO |
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Gene:
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Foxp3
Location:
ChrX:7579676-7595243 bp, + strand
Genetic Position: ChrX,
3.41 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:82560
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: A floxed fragment encompassing exons 1 through 5 was deleted via cre mediated recombination in the germline. (J:82560)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Foxp3 Mutation:
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23 strains or lines available |
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| References |
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Original: |
J:82560
Fontenot JD et al.,
"Foxp3 programs the development and function of CD4+CD25+ regulatory T cells."
Nat Immunol 2003 Apr;4(4):330-6
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All: |
27 reference(s)
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Analysis Tools
