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| Nomenclature |
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Symbol:
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Disp1icb
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Name:
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dispatched homolog 1 (Drosophila);
icbins
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MGI ID: |
MGI:2448055 |
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Synonyms: |
Disp1C829F |
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Gene:
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Disp1
Location:
Chr1:183086264-183221529 bp, - strand
Genetic Position: Chr1,
Syntenic
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: The mutation in the icbins mouse was identified as a G to T transversion that changed a cysteine to a phenylalanine at amino acid position 829. This mutation affects a predicted extracellular loop containing 6 highly conserved cysteine residues. (J:79027)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Disp1 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:79027
Caspary T et al.,
"Mouse dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling."
Curr Biol 2002 Sep 17;12(18):1628-32
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All: |
6 reference(s)
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Analysis Tools
