Tg(MMTV-Myc)141-3Led
Transgene Detail
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| Nomenclature |
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Symbol:
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Tg(MMTV-Myc)141-3Led
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Name:
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transgene insertion 141-3, Philip Leder
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MGI ID: |
MGI:2447500 |
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Synonyms: |
141-3, M strain, MTV-H3 141-3, TG.M |
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Transgene:
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Tg(MMTV-Myc)141-3Led
Location:
unknown
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Transgene origin |
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Strain of Origin:
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(CD-1 x C57BL/6J)F1
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene contains the MMTV (mouse mammary tumor virus) promoter and the mouse Myc (myelocytomatosis) oncogene. The construct is also called "MTV-H3 myc." The transgene was expressed in salivary gland, intestine, and mammary gland. Expression of the transgene was not detected in thymus, pancreas, spleen, kidney, testis, liver, heart, lung, muscle, brain, or preputial gland. (J:29013)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Lines 139-1, 143-3, and 143-5 also carry this construct. The construct is also called "MMTV/c-myc'" "MTV-H3" "MTV-H3 myc" or "MMTV-H3 myc" or "TG.M."
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| References |
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Original: |
J:29013
Stewart TA et al.,
"Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes."
Cell 1984 Oct;38(3):627-37
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All: |
27 reference(s)
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