|
|
| Nomenclature |
|
Symbol:
|
Tg(SFTPC-rtTA)5Jaw
|
|
Name:
|
transgene insertion 5, Jeffrey A Whitsett
|
|
MGI ID: |
MGI:2445716 |
|
Synonyms: |
hSPC-rtTA+, SFTPC-rtTA, Sp-c-rtta, SP-CrtTA, SPC-rtTA, SP-C-rtTA mice (Line 1), SP-C-rtTAtg, SP-CrtTAtg, Tg(SFTPC-rtTA)1Jaw |
|
Transgene:
|
Tg(SFTPC-rtTA)5Jaw
Location:
unknown
|
|
Transgene
origin |
|
Strain of Origin:
|
Not Specified
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The transgene is composed of 3.7 kb of human SFTPC promoter, a reverse tetracycline responsive transactivator gene (rt-TA), and a 0.45 kb SV40 polyadenylation signal. Transgene expression was confirmed by RT-PCR analysis. The human SFTPC promoter is active in respiratory epithelial cells. (J:61736)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:61736
Tichelaar JW et al.,
"Conditional expression of fibroblast growth factor-7 in the developing and mature lung."
J Biol Chem 2000 Apr 21;275(16):11858-64
|
|
All: |
86 reference(s)
|
|
Analysis Tools
