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| Nomenclature |
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Symbol:
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Map6tm1Job
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Name:
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microtubule-associated protein 6;
targeted mutation 1, Didier Job
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MGI ID: |
MGI:2388040 |
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Synonyms: |
STOP- |
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Gene:
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Map6
Location:
Chr7:99267447-99337136 bp, + strand
Genetic Position: Chr7,
54.05 cM, cytoband E2-F1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:79099
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: Exon 1 was disrupted with a cassette containing lacZ and neo genes. Protein was undetected by Western blot analysis of brain extracts from homozygous mutant mice. (J:79099)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Map6 Mutation:
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4 strains or lines available |
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Notes |
ES cell line = R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+) or AT1 ((129S2/SvPasIco, now called 129S2/SvPasCrl by Charles River).
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| References |
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Original: |
J:79099
Andrieux A et al.,
"The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders."
Genes Dev 2002 Sep 15;16(18):2350-64
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All: |
10 reference(s)
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Analysis Tools
