Tg(Fabp4-cre)1Rev
Transgene Detail
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| Nomenclature |
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Symbol:
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Tg(Fabp4-cre)1Rev
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Name:
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transgene insertion 1, Ronald M Evans
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MGI ID: |
MGI:2386686 |
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Synonyms: |
aP2-CRE, FABP4-Cre |
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Transgene:
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Tg(Fabp4-cre)1Rev
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: Sequence encoding cre recombinase was adjoined to the Fabp4 promoter, which is active in white and brown adipose tissue. Northern blot analysis and a functional assay showed the transgene to be abundantly expressed in brown and white adipose tissue. Significant expression was not detected in other tissues including skeletal muscle, liver, and heart. (J:73557, J:88210)
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Recombinase activity
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Activity in:
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adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities & their linings,
endocrine system,
hemolymphoid system,
integumental system,
limbs,
liver & biliary system,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal & urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system,
tail
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Not detected in:
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embryo-other,
extraembryonic component
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Driver:
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Fabp4
Summary of all recombinase alleles
driven by Fabp4.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:73557
Barak Y et al.,
"Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer."
Proc Natl Acad Sci U S A 2002 Jan 8;99(1):303-8
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All: |
56 reference(s)
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Analysis Tools
