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| Nomenclature |
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Symbol:
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Ppardtm1.1Rev
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Name:
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peroxisome proliferator activator receptor delta;
targeted mutation 1.1, Ronald M Evans
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MGI ID: |
MGI:2386684 |
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Synonyms: |
Ppardelta- |
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Gene:
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Ppard
Location:
Chr17:28232754-28301469 bp, + strand
Genetic Position: Chr17,
14.64 cM
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Pathologies of Ppardtm1.1Rev/Ppardtm1.1Rev mouse placentas
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:73557
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Exon 4, which encodes the amino terminal portion of the DNA binding domain was excised along with a downstream neo cassette via the expression of cre recombinase in vitro. (J:73557)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ppard Mutation:
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46 strains or lines available |
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| References |
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Original: |
J:73557
Barak Y et al.,
"Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer."
Proc Natl Acad Sci U S A 2002 Jan 8;99(1):303-8
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All: |
10 reference(s)
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Analysis Tools
