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| Nomenclature |
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Symbol:
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Tg(Otog-cre)1Ugds
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Name:
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transgene insertion 1, Unite de Genetique des Deficits Sensoriels
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MGI ID: |
MGI:2183511 |
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Synonyms: |
Otog-cre, Tg(Otog-cre)1Ptt |
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Transgene:
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Tg(Otog-cre)1Ugds
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: The transgenic construct was generated by inserting sequence encoding NLS-cre recombinase into a BAC encompassing the 5' portion of the murine Otog gene. Otog is endogenously expressed in the inner ear. Cre was flanked upstream by the Otog promoter and UTR of exon 1 and downstream by the coding region of exon 1 and all of exon 2. (J:77823)
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Recombinase activity
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Driver:
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Otog
Summary of all recombinase alleles
driven by Otog.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:77823
Cohen-Salmon M et al.,
"Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell death."
Curr Biol 2002 Jul 9;12(13):1106-11
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All: |
2 reference(s)
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Analysis Tools
