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| Nomenclature |
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Symbol:
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Fancatm1Faw
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Name:
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Fanconi anemia, complementation group A;
targeted mutation 1, Fre Arwert
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MGI ID: |
MGI:2183470 |
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Synonyms: |
Fanca- |
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Gene:
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Fanca
Location:
Chr8:123268300-123318576 bp, - strand
Genetic Position: Chr8,
72.1 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:63742
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 4 through 7 were deleted by the insertion of a cassette comprised of a splice acceptor site, IRES-lacZ, and neo. Protein was undetected in homozygous mutant mice via Western blot analysis of splenic tissue. (J:63742)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fanca Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:63742
Cheng NC et al.,
"Mice with a targeted disruption of the fanconi anemia homolog fanca"
Hum Mol Genet 2000 Jul 22;9(12):1805-11
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All: |
10 reference(s)
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Analysis Tools
