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| Nomenclature |
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Symbol:
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Gata3tm1Gsv
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Name:
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GATA binding protein 3;
targeted mutation 1, Frank Grosveld
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MGI ID: |
MGI:2181200 |
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Synonyms: |
G3-KI, Gata2nlslacZ, Gata3LacZ, GATA-3nlslacZ, Gata3z |
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Gene:
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Gata3
Location:
Chr2:9857078-9890034 bp, - strand
Genetic Position: Chr2,
6.69 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:77126
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 2 was disrupted by the insertion of a cassette containing PGK-hygro and NLS-lacZ at the translational start codon. The majority of exon 2 was deleted. (J:77126)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gata3 Mutation:
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3 strains or lines available |
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Notes |
ES cell line = AB1 (129S7/SvEvBrd-Hprt+) or E14 (129P2/OlaHsd).
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| References |
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Original: |
J:77126
van Doorninck JH et al.,
"GATA-3 is involved in the development of serotonergic neurons in the caudal raphe nuclei."
J Neurosci 1999 Jun 15;19(12):RC12
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All: |
17 reference(s)
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Analysis Tools
