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| Nomenclature |
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Symbol:
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Tcratm1Mjo
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Name:
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T cell receptor alpha chain;
targeted mutation 1, Michael J Owen
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MGI ID: |
MGI:2180883 |
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Synonyms: |
Calpha-, Tcralpha-, TCRalpha, TCRalphae-, TCRalpha KO |
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Gene:
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Tcra
Location:
unknown
Genetic Position: Chr14,
cytoband D1-D2
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:1292
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Parent Cell Line:
| GK129 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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The Tcra-C element C1 was disrupted by the insertion of a neomycin selection cassette. (J:1292)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:1292
Philpott KL et al.,
"Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells."
Science 1992 Jun 5;256(5062):1448-52
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All: |
71 reference(s)
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