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Tcratm1Mjo
Targeted Allele Detail

Nomenclature
Symbol: Tcratm1Mjo
Name: T cell receptor alpha chain; targeted mutation 1, Michael J Owen
MGI ID: MGI:2180883
Synonyms: Calpha-, Tcralpha-, TCRalpha, TCRalphae-, TCRalpha KO
Gene: Tcra   Location: unknown     Genetic Position: Chr14, cytoband D1-D2
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:1292
Parent Cell Line: GK129 (ES Cell)
Strain of Origin: 129P2/OlaHsd
Mutation
description
Allele Type:   Targeted (knock-out)
Mutation:   Insertion
    The Tcra-C element C1 was disrupted by the insertion of a neomycin selection cassette. (J:1292)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Tcra Mutation: 62 strains or lines available
References
Original: J:1292 Philpott KL et al., "Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells." Science 1992 Jun 5;256(5062):1448-52
All: 71 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory