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| Nomenclature |
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Symbol:
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Nodaltm1Rob
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Name:
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nodal;
targeted mutation 1, Elizabeth J Robertson
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MGI ID: |
MGI:2180793 |
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Synonyms: |
Nodal-, nodal-KO, nodallacZ, nodal.lacZ |
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Gene:
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Nodal
Location:
Chr10:61417972-61425338 bp, + strand
Genetic Position: Chr10,
32.21 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:32935
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Parent Cell Line:
| CCE/EK.CCE (ES Cell) |
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Strain of Origin:
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129S/SvEv-Gpi1c
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 400 bp segment from the second exon was replaced with an IRES-lacZ and neomycin gene fusion cassette. Beta-galactosidase was expressed from this allele under the control of the endogenous promoter. (J:32935, J:48467)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:32935
Collignon J et al.,
"Relationship between asymmetric nodal expression and the direction of embryonic turning."
Nature 1996 May 9;381(6578):155-8
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All: |
50 reference(s)
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Analysis Tools
