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| Nomenclature |
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Symbol:
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Lamb3IAP
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Name:
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laminin, beta 3;
intracisternal-A particle insertion
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MGI ID: |
MGI:2179716 |
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Gene:
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Lamb3
Location:
Chr1:193301957-193343878 bp, + strand
Genetic Position: Chr1,
97.71 cM, cytoband H2-H6
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Control and Lamb3IAP/Lamb3IAP histological skin section.
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Transposon insertion |
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Mutation details: An intracisternal-A particle was found to be inserted into the gene at the 3' end of a 0.55 kb intron at the intron/exon junction. Northern blot analysis on embryonic RNA demonstrated that no detectable transcript was expressed from this allele. (J:42382)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Lamb3 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:42382
Kuster JE et al.,
"IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa."
Mamm Genome 1997 Sep;8(9):673-81
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All: |
1 reference(s)
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Analysis Tools
