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| Nomenclature |
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Symbol:
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Map3k1tm1Glj
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Name:
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mitogen-activated protein kinase kinase kinase 1;
targeted mutation 1, Gary L Johnson
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MGI ID: |
MGI:2179711 |
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Synonyms: |
MEKK1 - |
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Gene:
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Map3k1
Location:
Chr13:111746428-111808993 bp, - strand
Genetic Position: Chr13,
63.36 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:62909
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Parent Cell Line:
| CCE/EK.CCE (ES Cell) |
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Strain of Origin:
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129S/SvEv-Gpi1c
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance gene in the antisense orientation replaced 132 codons, including the ATG start site in exon 1. (J:62909)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:62909
Yujiri T et al.,
"MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation."
Proc Natl Acad Sci U S A 2000 Jun 20;97(13):7272-7
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All: |
5 reference(s)
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Analysis Tools
