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| Nomenclature |
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Symbol:
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Tbx1tm1Pa
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Name:
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T-box 1;
targeted mutation 1, Virginia Papaioannou
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MGI ID: |
MGI:2179190 |
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Gene:
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Tbx1
Location:
Chr16:18581713-18586969 bp, - strand
Genetic Position: Chr16,
11.51 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:70730
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
| |
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A loxP-flanked neomycin selection cassette replaced most of the coding region of the gene. (J:70730)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tbx1 Mutation:
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11 strains or lines available |
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| References |
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Original: |
J:70730
Jerome LA et al.,
"DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1."
Nat Genet 2001 Mar;27(3):286-91
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All: |
19 reference(s)
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Analysis Tools
