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| Nomenclature |
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Symbol:
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Col18a1tm1Hms
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Name:
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collagen, type XVIII, alpha 1;
targeted mutation 1, Harvard Medical School
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MGI ID: |
MGI:2179134 |
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Synonyms: |
Col18a1- |
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Gene:
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Col18a1
Location:
Chr10:77052178-77166548 bp, - strand
Genetic Position: Chr10,
39.72 cM, cytoband B5-C1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:75861
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A PGK/neo cassette replaces exons 17-38 of the endogenous locus. The insertion disrupts all variant forms from the locus. (J:75861)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Col18a1 Mutation:
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69 strains or lines available |
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| References |
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Original: |
J:75861
Fukai N et al.,
"Lack of collagen XVIII/endostatin results in eye abnormalities."
EMBO J 2002 Apr 2;21(7):1535-44
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All: |
21 reference(s)
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Analysis Tools
