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| Nomenclature |
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Symbol:
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Nyxnob
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Name:
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nyctalopin;
no b wave
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MGI ID: |
MGI:2177945 |
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Synonyms: |
nob |
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Gene:
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Nyx
Location:
ChrX:13466110-13489313 bp, + strand
Genetic Position: ChrX,
8.37 cM
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Mutation
origin |
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Strain of Origin:
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BALB/cGr-nr
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Intragenic deletion |
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Mutation details: The mutation in the nob mouse was identified as an 85 bp deletion in exon 3 of the gene. The deletion results in a frame shift that adds 170 unique amino acids to 188 amino acids from the amino terminus of the protein. This results in the loss of 288 amino acids fro the carboxyl terminus of the protein including seven leucine rich repeats. (J:81028)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Nyx Mutation:
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0 strains or lines available |
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Notes |
Arose spontaneously on BALB/cGr-nr/nr (nervous) and then transferred to BALB/cByJ inbred strain (J:50824).
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| References |
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Original: |
J:50824
Pardue MT et al.,
"A naturally occurring mouse model of X-linked congenital stationary night blindness."
Invest Ophthalmol Vis Sci 1998 Nov;39(12):2443-9
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All: |
12 reference(s)
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Analysis Tools
