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| Nomenclature |
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Symbol:
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Engtm1Dyl
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Name:
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endoglin;
targeted mutation 1, Dean Y Li
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MGI ID: |
MGI:2177823 |
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Synonyms: |
Eng- |
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Gene:
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Eng
Location:
Chr2:32646595-32682658 bp, + strand
Genetic Position: Chr2,
22.09 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:55403
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
| |
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A neomycin resistance cassette replaced the first two exons of the gene. (J:55403)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Eng Mutation:
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15 strains or lines available |
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| References |
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Original: |
J:55403
Li DY et al.,
"Defective angiogenesis in mice lacking endoglin."
Science 1999 May 28;284(5419):1534-7
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All: |
3 reference(s)
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Analysis Tools
