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| Nomenclature |
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Symbol:
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Runx2tm1Mjo
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Name:
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runt related transcription factor 2;
targeted mutation 1, Michael J Owen
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MGI ID: |
MGI:2176465 |
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Synonyms: |
Cbfa1-, Runx2- |
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Gene:
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Runx2
Location:
Chr17:44495987-44814797 bp, - strand
Genetic Position: Chr17,
21.33 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:40784
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: Insertion of an IRES-lacZ-neomycin resistance cassette into the exon encoding the Q/A repeat domain placed lacZ under the control of the endogenous promoter. (J:40784)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Runx2 Mutation:
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3 strains or lines available |
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Notes |
ES cell line = GK129 and R1.3
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| References |
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Original: |
J:40784
Otto F et al.,
"Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development [see comments]"
Cell 1997 May 30;89(5):765-71
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All: |
35 reference(s)
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Analysis Tools
