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| Nomenclature |
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Symbol:
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Pou4f3tm1Rsd
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Name:
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POU domain, class 4, transcription factor 3;
targeted mutation 1, Michael G Rosenfeld
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MGI ID: |
MGI:2176270 |
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Synonyms: |
Brn3.1- |
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Gene:
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Pou4f3
Location:
Chr18:42394539-42397249 bp, + strand
Genetic Position: Chr18,
22.58 cM, cytoband B3-E1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:33502
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin selection cassette replaced a 2.4 kb genomic fragment containing the entire coding sequence of the gene. In situ hybridization analysis confirmed absence of mRNA in trigeminal ganglia of mutant mice. (J:33502)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pou4f3 Mutation:
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5 strains or lines available |
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Notes |
Homozygous mutant mice have a similar phenotype to dreidel mice, which are homozygous for Pou4f3ddl.
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| References |
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Original: |
J:33502
Erkman L et al.,
"Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development."
Nature 1996 Jun 13;381(6583):603-6
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All: |
4 reference(s)
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Analysis Tools
