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| Nomenclature |
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Symbol:
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Irf2tm1Mak
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Name:
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interferon regulatory factor 2;
targeted mutation 1, Tak Mak
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MGI ID: |
MGI:2175949 |
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Synonyms: |
IRF-2- |
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Gene:
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Irf2
Location:
Chr8:46739745-46847458 bp, + strand
Genetic Position: Chr8,
26.42 cM, cytoband B2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:64286
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced the third exon of the gene, which encodes amino acids 30 - 63, part of the DNA-binding domain of the protein. (J:64286)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Irf2 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:64286
Matsuyama T et al.,
"Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development."
Cell 1993 Oct 8;75(1):83-97
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All: |
23 reference(s)
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Analysis Tools
