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| Nomenclature |
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Symbol:
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Bmpr2tm1Kmi
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Name:
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bone morphogenetic protein receptor, type II (serine/threonine kinase);
targeted mutation 1, Kohei Miyazono
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MGI ID: |
MGI:2158503 |
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Gene:
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Bmpr2
Location:
Chr1:59764637-59870859 bp, + strand
Genetic Position: Chr1,
30.44 cM, cytoband C2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:61931
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin selection cassette replaced a genomic fragment containing exons 4 and 5. These sequences encode the transmembrane domain and the amino terminal region of the kinase domain. (J:61931)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Bmpr2 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:61931
Beppu H et al.,
"BMP type II receptor is required for gastrulation and early development of mouse embryos."
Dev Biol 2000 May 1;221(1):249-58
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All: |
10 reference(s)
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Analysis Tools
