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| Nomenclature |
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Symbol:
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MecomJbo
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Name:
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MDS1 and EVI1 complex locus;
Junbo
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MGI ID: |
MGI:2158381 |
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Synonyms: |
Jbo, Junbo |
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Gene:
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Mecom
Location:
Chr3:29951299-30548008 bp, - strand
Genetic Position: Chr3,
12.66 cM
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Polydactyly in MecomJbo/Evi1+ and MecomJbo/MecomJbo mice
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: The mutation was shown by sequence analysis to be an A2288T transversion in the gene causing a nonconservative Asn763Ile change in the second of the two zinc-finger domains in the encoded protein. (J:113445)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:113445
Parkinson N et al.,
"Mutation at the Evi1 locus in Junbo mice causes susceptibility to Otitis media"
PLoS Genet 2006;2(10):e149
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All: |
4 reference(s)
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Analysis Tools
