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| Nomenclature |
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Symbol:
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Lumtm1Chak
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Name:
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lumican;
targeted mutation 1, Shukti Chakravarti
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MGI ID: |
MGI:2153008 |
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Synonyms: |
Lum-, lumtm1Sc |
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Gene:
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Lum
Location:
Chr10:97565501-97572703 bp, + strand
Genetic Position: Chr10,
50.32 cM
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Fmodtm1Aol/Fmodtm1Aol Lumtm1Chak/Lumtm1Chak mice display decreased body size, abnormal gait and abnormal limb morphology
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:48068
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A neomycin resistance cassette replaced 3kb of sequence containing exon 2. (J:48068)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Lum Mutation:
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2 strains or lines available |
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Notes |
ES cell line = CT 120#25.
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| References |
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Original: |
J:48068
Chakravarti S et al.,
"Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican."
J Cell Biol 1998 Jun 1;141(5):1277-86
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All: |
16 reference(s)
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Analysis Tools
