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| Nomenclature |
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Symbol:
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Scaptm1Mbjg
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Name:
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SREBF chaperone;
targeted mutation 1, Joseph L Goldstein
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MGI ID: |
MGI:2148743 |
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Synonyms: |
Scap-, SCAPflox, Scaptm1Gsn |
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Gene:
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Scap
Location:
Chr9:110333288-110384946 bp, + strand
Genetic Position: Chr9,
59.91 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:69592
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Parent Cell Line:
| SM1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A a loxP-flanked neomycin resistance cassette located 3 kb upstream of exon 1. An additional loxP site was inserted in intron 1. (J:69592)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:69592
Matsuda M et al.,
"SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation."
Genes Dev 2001 May 15;15(10):1206-16
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All: |
9 reference(s)
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Analysis Tools
