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| Nomenclature |
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Symbol:
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FlnaDilp2
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Name:
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filamin, alpha;
dilated pupils 2
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MGI ID: |
MGI:1934627 |
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Synonyms: |
GENA 379 |
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Gene:
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Flna
Location:
ChrX:74223461-74249820 bp, - strand
Genetic Position: ChrX,
37.89 cM
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Mutation
origin |
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Strain of Origin:
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(C3H/HeN x BALB/cAnN)F1
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at Harwell. A single T to A transversion is found in exon 44 at position 7164. This converts a tyrosine codon to a nonsense codon at position 2388 in the protein. (J:112274)
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Inheritance: | |
Semidominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:75964
Thaung C et al.,
"Novel ENU-induced eye mutations in the mouse: models for human eye disease."
Hum Mol Genet 2002 Apr 1;11(7):755-67
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All: |
4 reference(s)
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Analysis Tools
