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| Nomenclature |
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Symbol:
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Ntf5tm1Par
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Name:
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neurotrophin 5;
targeted mutation 1, Luis F Parada
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MGI ID: |
MGI:1933845 |
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Synonyms: |
NT-4 -, NT-4/5 KO |
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Gene:
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Ntf5
Location:
Chr7:45413695-45417178 bp, + strand
Genetic Position: Chr7,
29.3 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:60927
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A PGK-neomycin resistance cassette replaced the entire coding region. In situ studies confirmed that no detectable transcript was expressed in DRG neurons of homozygous mutant neonates. (J:60927)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ntf5 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:60927
Liebl DJ et al.,
"Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice."
Proc Natl Acad Sci U S A 2000 Feb 29;97(5):2297-302
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All: |
6 reference(s)
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Analysis Tools
