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| Nomenclature |
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Symbol:
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CrygeAey1
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Name:
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crystallin, gamma E;
nuclear and zonular cataract
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MGI ID: |
MGI:1932397 |
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Gene:
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Cryge
Location:
Chr1:65048554-65051149 bp, - strand
Genetic Position: Chr1,
32.8 cM
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Mutation
origin |
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Strain of Origin:
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C3HeB/FeJ
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: A transversion of an A at position 1 of the cDNA to a T. This results in expression from an ATG 19 bp downstream. The phase of this ORF is shifted +1 to produce a novel protein, which may interfere with the normal structural organization of the lens. (J:67888)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cryge Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:68708
Hrabe de Angelis MH et al.,
"Genome-wide, large-scale production of mutant mice by ENU mutagenesis."
Nat Genet 2000 Aug;25(4):444-7
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All: |
3 reference(s)
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Analysis Tools
