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| Nomenclature |
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Symbol:
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Cd36tm1Mfe
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Name:
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CD36 antigen;
targeted mutation 1, Maria Febbraio
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MGI ID: |
MGI:1931790 |
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Synonyms: |
Cd36-, CD36KO, CD36 KO, FAT/CD36- |
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Gene:
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Cd36
Location:
Chr5:17781690-17888959 bp, - strand
Genetic Position: Chr5,
8.11 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:56081
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A neomycin cassette replaced a 1kb fragment including the transcription start site. (J:56081)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:56081
Febbraio M et al.,
"A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism."
J Biol Chem 1999 Jul 2;274(27):19055-62
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All: |
91 reference(s)
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