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| Nomenclature |
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Symbol:
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Csf2tm1Mlg
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Name:
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colony stimulating factor 2 (granulocyte-macrophage);
targeted mutation 1, Richard C Mulligan
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MGI ID: |
MGI:1930996 |
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Synonyms: |
Csf2-, GM-, GM-CSF-, GM-CSF KO |
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Gene:
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Csf2
Location:
Chr11:54247271-54249667 bp, - strand
Genetic Position: Chr11,
32.13 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:17978
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Exons 3 and 4 and flanking intronic sequence were replaced by a neomycin cassette. (J:17978)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Csf2 Mutation:
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11 strains or lines available |
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| References |
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Original: |
J:17978
Dranoff G et al.,
"Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis."
Science 1994 Apr 29;264(5159):713-6
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All: |
51 reference(s)
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