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| Nomenclature |
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Symbol:
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Pdgfratm2Sor
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Name:
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platelet derived growth factor receptor, alpha polypeptide;
targeted mutation 2, Philippe Soriano
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MGI ID: |
MGI:1926728 |
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Synonyms: |
alphaR2-4, alphaR4 |
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Gene:
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Pdgfra
Location:
Chr5:75152291-75198204 bp, + strand
Genetic Position: Chr5,
39.55 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:41814
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Parent Cell Line:
| AK7 (ES Cell) |
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Strain of Origin:
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129S4/SvJaeSor
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Replacement of intronic sequences encoding the signal peptide, and the first and second immunoglobulin domains with a loxP-flanked neomycin cassette. (J:41814)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pdgfra Mutation:
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8 strains or lines available |
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| References |
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Original: |
J:41814
Soriano P,
"The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites."
Development 1997 JUL;124(14):2691-2700
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All: |
8 reference(s)
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Analysis Tools
