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| Nomenclature |
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Symbol:
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Itgb6tm1Des
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Name:
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integrin beta 6;
targeted mutation 1, Dean Sheppard
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MGI ID: |
MGI:1926484 |
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Synonyms: |
beta6-, Itgb6- |
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Gene:
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Itgb6
Location:
Chr2:60598292-60722643 bp, - strand
Genetic Position: Chr2,
34.81 cM, cytoband C3
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Juvenile baldness in Itgb6tm1Des/Itgb6tm1Des mice
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:33139
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Parent Cell Line:
| RF8 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Insertion of a neomycin gene into a coding exon of the Itgb6 gene. (J:33139)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Itgb6 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:33139
Huang XZ et al.,
"Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin."
J Cell Biol 1996 May;133(4):921-8
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All: |
23 reference(s)
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Analysis Tools
