Lrp8<tm1Her> Targeted Allele Detail MGI Mouse (MGI:1861964)

Lrp8^tm1Her
Targeted Allele Detail

Nomenclature

Symbol:	Lrp8^tm1Her
Name:	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; targeted mutation 1, Joachim Herz
MGI ID:	MGI:1861964
Synonyms:	ApoER2-
Gene:	Lrp8 Location: Chr4:107802261-107876840 bp, + strand Genetic Position: Chr4, 50.18 cM, cytoband C7

Disruption of hippocampal layers in Lrp8^tm1Her/Lrp8^tm1Her, Pafah1b1^tm1Awb/Pafah1b1⁺, and Lrp8^tm1Her/Lrp8^tm1Her Pafah1b1^tm1Awb/Pafah1b1⁺ mice

Show the 1 image(s) involving this allele.

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:55691
Parent Cell Line:	SM1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Mutation
description

Allele Type:		Targeted (knock-out)
Mutations:		Insertion, Intragenic deletion
		Mutation details

Phenotypes

View phenotypes for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)

Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Lrp8 Mutation:	3 strains or lines available

References

Original:	J:55691 Trommsdorff M et al., "Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2." Cell 1999 Jun 11;97(6):689-701
All:	36 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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