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| Nomenclature |
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Symbol:
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Slc30a3tm1Rpa
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Name:
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solute carrier family 30 (zinc transporter), member 3;
targeted mutation 1, Richard D Palmiter
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MGI ID: |
MGI:1859820 |
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Synonyms: |
Znt3-, ZnT3 |
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Gene:
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Slc30a3
Location:
Chr5:31086106-31093615 bp, - strand
Genetic Position: Chr5,
16.97 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:53059
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 1 through 4 were replaced with a cassette containing nuclear lacZ and neo. Encoded protein was undetectable in brain homogenates from homozygous mutant mice via Western blot analysis. Beta-galactosidase expression was used to observe the activity of the endogenous promoter. (J:53059)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:53059
Cole TB et al.,
"Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene."
Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1716-21
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All: |
17 reference(s)
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Analysis Tools
