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Mlh1tm1Lisk
Targeted Allele Detail

Nomenclature
Symbol: Mlh1tm1Lisk
Name: mutL homolog 1 (E. coli); targeted mutation 1, Michael Liskay
MGI ID: MGI:1857946
Synonyms: Mlh1-
Gene: Mlh1   Location: Chr9:111228228-111271608 bp, - strand    Genetic Position: Chr9, 60.92 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:34291
Parent Cell Line: AB2.2 (ES Cell)
Strain of Origin: 129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:   Targeted (knock-out)
Mutations:   Insertion, Intragenic deletion
    Replacement of exon 4 with a Pgk-HPRT mini-gene. (J:34291)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Mlh1 Mutation: 11 strains or lines available
References
Original: J:34291 Baker SM et al., "Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over [see comments]" Nat Genet 1996 Jul;13(3):336-42
All: 39 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/22/2013
MGI 5.13
The Jackson Laboratory