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| Nomenclature |
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Symbol:
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Hoxd13tm1Ddu
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Name:
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homeobox D13;
targeted mutation 1, Denis Duboule
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MGI ID: |
MGI:1857871 |
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Synonyms: |
Hoxd-13-, Hoxd-13St |
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Gene:
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Hoxd13
Location:
Chr2:74668310-74671599 bp, + strand
Genetic Position: Chr2,
44.13 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:15507
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A neomycin cassette was inserted into the sequences encoding the 11th amino acid of the homeobox domain. (J:15507)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hoxd13 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:15507
Dolle P et al.,
"Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs."
Cell 1993 Nov 5;75(3):431-41
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All: |
11 reference(s)
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Analysis Tools
