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| Nomenclature |
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Symbol:
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Abca4tm1Ght
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Name:
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ATP-binding cassette, sub-family A (ABC1), member 4;
targeted mutation 1, Gabriel H Travis
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MGI ID: |
MGI:1857860 |
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Synonyms: |
abcr- |
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Gene:
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Abca4
Location:
Chr3:122044443-122180061 bp, + strand
Genetic Position: Chr3,
52.94 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:56317
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Replacement of a 4 kb genomic fragment containing the promoter and first exon with a neomycin cassette. Immunoblot analysis of retinal homogenates failed to detect any protein in samples derived from homozygous mice. (J:56317)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Abca4 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:56317
Weng J et al.,
"Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice."
Cell 1999 Jul 9;98(1):13-23
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All: |
31 reference(s)
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Analysis Tools
