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| Nomenclature |
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Symbol:
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Hoxb1tm3Mrc
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Name:
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homeobox B1;
targeted mutation 3, Mario R Capecchi
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MGI ID: |
MGI:1857859 |
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Synonyms: |
Hoxb1BloxP |
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Gene:
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Hoxb1
Location:
Chr11:96365752-96368256 bp, + strand
Genetic Position: Chr11,
59.86 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:41540
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Replacement of a 371 bp BglII fragment of exon 2 with a loxP-flanked neomycin cassette and an insertion of a 12 bp linker into exon 1. The neomycin cassette was removed via Cre-mediated recombination in the final allele. (J:41540)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hoxb1 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:41540
Rossel M et al.,
"Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development."
Development 1999 Nov;126(22):5027-40
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All: |
2 reference(s)
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Analysis Tools
