|
|
| Nomenclature |
|
Symbol:
|
Foxc2tm1Miu
|
|
Name:
|
forkhead box C2;
targeted mutation 1, Naoyuki Miura
|
|
MGI ID: |
MGI:1857740 |
|
Synonyms: |
Mfh1-, MFH-1- |
|
Gene:
|
Foxc2
Location:
Chr8:121116171-121118892 bp, + strand
Genetic Position: Chr8,
70.33 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:55316
|
|
Parent Cell Line:
| E14.1 (ES Cell) |
|
Strain of Origin:
|
129P2/OlaHsd
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A neomycin resistance cassette replaced a genomic fragment containing the entire coding region of the gene. RT-PCR analysis on RNA derived from E11.5 homozygous embryos confirmed that no detectable transcript was produced from this allele. (J:55316)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Foxc2 Mutation:
|
0 strains or lines available |
|
| References |
|
Original: |
J:55316
Iida K et al.,
"Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis."
Development 1997 Nov;124(22):4627-38
|
|
All: |
11 reference(s)
|
|
Analysis Tools
