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| Nomenclature |
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Symbol:
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Rac1tm1Jms
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Name:
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RAS-related C3 botulinum substrate 1;
targeted mutation 1, Institute of Medical Science, Japan
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MGI ID: |
MGI:1857700 |
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Gene:
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Rac1
Location:
Chr5:143505478-143528036 bp, - strand
Genetic Position: Chr5,
82.22 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:52224
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Parent Cell Line:
| CCE/EK.CCE (ES Cell) |
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Strain of Origin:
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129S/SvEv-Gpi1c
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neo-gpt cassette replaced a genomic fragment containing exons E1 and E2. These exons encode amino acids 97-192 of the protein. (J:52224)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Rac1 Mutation:
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12 strains or lines available |
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| References |
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Original: |
J:52224
Sugihara K et al.,
"Rac1 is required for the formation of three germ layers during gastrulation."
Oncogene 1998 Dec 31;17(26):3427-33
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All: |
3 reference(s)
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Analysis Tools
